Radiation-Induced Adaptive Responses and Bystander Effects
نویسندگان
چکیده
منابع مشابه
Radiation-induced adaptive responses and bystander effects.
A classical paradigm [correction of paradym] of radiation biology asserts that all radiation effects on cells, tissues and organisms are due to the direct action of radiation. However, there has been a recent growth of interest in the indirect actions of radiation including the radiation-induced adaptive response, the bystander effect, low-dose hypersensitivity, and genomic instability, which a...
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I onizing radiation fills the universe. Daily ionizing particles and rays collide with molecules in 1% of the 100 trillion cells that make up the average human. These collisions generate clusters of free radicals known as reactive oxygen species that randomly damage cellular constituents including DNA (1). Certain types of ionizing radiation are more effective at generating reactive oxygen spec...
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Introduction: Radiation effects observed in cells that are not irradiated are known as non-targeted effects. Radiation induced bystander effect (RIBE) as a kind of non-targeted effect has been introduced in recent years. RIBE occurs in unexposed cells which are related to adjacent or distant irradiated cells. RIBE contradict with "target theory" which necessitates radiation tr...
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Introduction: Radiation Induced Bystander Effect (RIBE) which cause radiation effects in non-irradiated cells, has challenged the principle according to which radiation traversal through the nucleus of a cell is necessary for producing biological responses. What is the mechanism of this phenomenon? To have a better understanding of this rather ambiguous concept substantial number of original ...
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The risks of exposure to low dose ionizing radiation (below 100 mSv) are estimated by extrapolating from data obtained after exposure to high dose radiation, using a linear no-threshold model (LNT model). However, the validity of using this dose-response model is controversial because evidence accumulated over the past decade has indicated that living organisms, including humans, respond differ...
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ژورنال
عنوان ژورنال: Biological Sciences in Space
سال: 2004
ISSN: 0914-9201,1349-967X
DOI: 10.2187/bss.18.247